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revealed that intratumoral STING signaling activation suppresses tumor angiogenesis and induces vessel normalization through type I IFN signaling activation and the upregulation of genes related to vascular normalization and endothelial-lymphocyte interaction

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10.1016/0016-5085(79)90235-x 58 RuenziM.StolteM.VeljacaM.OreskovicK.PetersonJ.Ulcerative Colitis Study Group (2005)

Additionally, experiments conducted on isolated bovine chondrocytes revealed an upregulation in the production of proteoglycans and collagen, fundamental components of the extracellular matrix essential for cartilage integrity