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Because attained semaglutide dose appeared to align more closely with cardiovascular outcomes than maximum achieved weight loss, the researchers explored whether the drug might exert direct effects on the heart

Discussion 1) This study performed by researchers Pan et al developed an efficient and cost-effective small-molecule strategy for generating functional hepatic cells from hPSCs, demonstrating its potential for cell-based therapy and drug discovery

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144 Pre-menstrual syndrome (PMS) The above review 144 also looked at the effects of magnesium on anxiety as a symptom of PMS, and found that four out of the seven relevant studies showed a positive effect of magnesium either on its own or in combination with vitamin B6, but also noted a number of methodological issues with the clinical trials reviewed

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Concurrently, reduced levels of glutathione (GSH) and inhibition of GPX4 activity weaken the antioxidant defense system, further promoting ferroptosis (Niu et al., 2023