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Is fever suppression involved in the etiology of autism and neurodevelopmental disorders

Furthermore, extensive research suggests that OS may impact cognitive function through various pathways, such as directly damaging parvalbumin-expressing interneurons (PVIs) (Schiavone et al., 2009), hindering oligodendrocyte precursor cell (OPC) proliferation and myelin formation in the prefrontal cortex (PFC) (Maas et al., 2021), disrupting the bloodbrain barrier (BBB) (Geng et al., 2023), and inducing mitochondrial dysfunction (Fizikova et al., 2023)

Despite the studys scarcity, calpains inhibition has been suggested as an attractive antitrypanosomatid approach even without the confirmation of their proteolytic activity in these parasites

10.3945/jn.109.114249 33 HartmannP.ChuH.DuanY.SchnablB

doi: 10.3390/cells9030561 138 PengMZhangQLiuYGuoXJuJXuLet al

Both supplements should complement evidence-based treatments under medical supervision and are not recommended as substitutes for conventional therapy in cardiovascular disease or chronic fatigue syndrome