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Description

Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels

PMID: 33947505

In the field of future mitochondrial-targeted drug development, several challenges remain

The pooled estimate of mean change in NAFLD activity score was -0.5 (95% CI -0.8 to -0.3, I 2 =32.0%) in patients without diabetes, and -1.5 (95% CI -2.1 to -0.9, I 2 =46.5%) in patients with diabetes