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Moreover, a higher percentage of patients were transplanted when treated with CPX-351 rather than with the 7 + 3 regimen (34% vs 25%), translating into a significant prolongation of OS (28)

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Certain medications, including altretamine, cisplatin, certain antibiotics like chloramphenicol, certain anti-seizure drugs (such as phenytoin), levodopa, and other vitamin/nutritional supplements, can interact with B vitamins

It follows a ping-pong mechanism

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Another objective test that can be used to assess CIPN in children is the Movement Assessment Battery for ChildrenSecond Edition (MABC-2), which is a functional test that has been developed to assess functional and motor impairment in children ( Combined subjective and objective assessments are tests that utilize questionnaires and combine these with functional, neurological, or electrophysiological assessments