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Powerful tools for the invivo investigation of local E GSH were developed in the form of redoxsensitive fluorescent proteins, rxYFP (Ostergaard et al , 2001, 2004) and the redoxsensitive green fluorescent proteins (roGFPs

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It is used to treat vitamin B12 deficiency, neuropathy, anemia, and general weakness

10 Discussion Our understanding of the pathomechanisms leading to CIPN have improved greatly in recent years