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Interestingly, in humans with B12 deficiency then, that's also been associated with dementia, which might explain why Elizabeth cat was constantly crying and vocalizing

NNMT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to nicotinamide, influencing intracellular nicotinamide availability and interacting with NAD-associated metabolic processes

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The research is relevant to drug-target discovery but does not establish a human strength, exercise-performance or healthy-ageing effect