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Funding This work was supported by the Natural Science Foundation of China (81803045, 82103277), the China Postdoctoral Science Foundation (2020M672072), the Research Project of Jinan Microecological Biomedicine Shandong Laboratory (JNL-2022041C), Shandong Excellent Young Scientists Fund Program (2022HWYQ-035), Shandong Provincial Natural Science Foundation (ZR2021QH030), and the Qilu Young Scholar Program of Shandong University, China

Samples were mixed with 10 native loading buffer (1.5 M Aminocaproic acid, 50 mM Bis-Tris, 0.5 mM, EDTA, 5% (w/v) Serva Blue G, pH 7.0) and electrophoresed on 310% self-cast gels