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People with RLS experience an irresistible urge to move their legs, which is typically accompanied by aching, itching, or crawling sensations

Accessed 1 May 2024 43.Moseley AM, Rahman P, Wells GA, Zadro JR, Sherrington C, Toupin-April K, Brosseau L

This is an important clarification because confusion sometimes arises from the fact that certain other diabetes medicationsparticularly metforminare well-documented to interfere with vitamin B12 absorption

Adequate intake of B12 prevents tingling sensations, numbness in hands and feet, and improves mobility

Researchers using AOD-9604 beyond that window are operating in an evidence gap