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The amount of water determines the final concentration (e.g., mg/mL) of your solution

However, the study was small, lacked a placebo control and evaluated biomarkers rather than long-term clinical outcomes

Available from: /pmc/articles/PMC5797268/ 44

It's important to note that the VitaPatch B12 patches are for external use only and have been specifically formulated with 500mcg of Vitamin B12 for optimal use