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Thus, the intestine-on-chip was able to recapitulate characteristic EED signatures, like upregulation of antimicrobial genes and downregulation of metallothioneins and genes involved in digestion and metabolism, providing a reliable tool for the disease study and drug testing, as well for developing a personalized therapy

doi: 10.3390/molecules24112076

Multi-omics integration analysis identifies lipid disorder of a non-alcoholic fatty liver disease (NAFLD) mouse model improved by Zexie-Baizhu decoction

ACS Nano 2019 , 13 , 39103923

The disease is characterised by autoimmune destruction of thyroid follicular cells through immune-mediated processes

doi: 10.1016/0142-9612(95)00310-X