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Trial interventions and procedures Surgery and implantable system A baseline visit assessed operability based on a complete workup (clinical examination, electrocardiogram, biological workup and chest X-ray) and brain magnetic resonance imaging

Brainstem and pontine dysplasia are rare phenotypes, with less than five patients reported [25]

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To further support the above argument, consider the adrenoleukodystrophy/adrenomyeloneuropathy disease spectrum