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IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

Science 302, 841

These flavanones, as well as pentahydroxyflavanone and eriodictyol, are common substrates for the synthetic branches leading to flavones, isoflavones, and phlobaphenes [200,201]

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Inflammatory mediators, ferroptosis inducers, mechanical overloading, and iron overload increase the accumulation of ROS and lipid peroxidation in chondrocytes, which can lead to chondrocytes ferroptosis and might contribute to the pathogenesis