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Consistently, in vitro data, including our findings, show that bacterially purified monomeric Syn WT also resists aggregation compared to PD-specific PTM-Syn variants 33,44,49 and remains inert unless its hydrophobic core is exposed 15,68

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Conformational dynamics of complement protease C1r inhibitor proteins from Lyme disease- and relapsing fever-causing spirochetes

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