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Noncancerous nodules may be managed through: Watchful waiting with regular monitoring Thyroid hormone therapy to suppress nodule growth Radioactive iodine, antithyroid medications, or beta blockers for nodules causing hyperthyroidism Cancerous thyroid nodules, large nodules causing compressive symptoms, or nodules with concerning features typically require surgical removal

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Both mitochondria and the ER maintain separate pools of GSH, independently regulated apart from the cytosolic GSH pool