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Increasing evidence suggests that the primary mechanism behind BBB leakage after a stroke is the breakdown of the TJ complex

Here, we show that positron emission tomography imaging with the system x c radiotracer, [ 18 F]FSPG, provides a sensitive and specific marker of NRF2 activation in orthotopic, patient-derived, and genetically engineered mouse models of NSCLC

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[5] Source: Spillers NJ, Talbot NC, Luther PM, Ly GH, Roberts CJ, Ahmadzadeh S, Shekoohi S, Viswanath O, Kaye AD

Once immobile, individual animals were removed from the chamber and placed on the bench with a nose cone that continued to deliver isofluorane