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Human clinical trial data are absent

Pregnant or Breastfeeding Women: The increased nutritional needs during pregnancy and breastfeeding may require B12 supplementation to support both mother and child

The figures below combine established pharmaceutical data and animal model extrapolation, labeled accordingly

BDNF signaling through postsynaptic TrkB receptors is essential for the insertion of AMPARs (AMPA-type receptors) for postsynaptic density and the development of mature synapses [61]

The oil of avocado consists of 71% MUFA, 13% PUFA, and 16% saturated fatty acidsa profile that has been shown to help promote healthy blood lipid profiles and enhance the bioavailability of fat-soluble vitamins and phytochemicals from the avocado or other fruits and vegetables, naturally low in fat, which are consumed with avocados. 2 It is not necessary to consume avocado oil to benefit from these potent fatty acids

Peters GJ, van der Wilt CL, van Moorsel CJ, Kroep JR, Bergman AM, Ackland SP