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The reaction was monitored by LC-MS (Supplementary Fig

4.1.1 Lipase inhibitors Lipase inhibitors, which modulate lipid metabolism to treat metabolic disorders, have shown potential in the management of various metabolic diseases

Mathien, S., Tesnire, C

(2004) Journal of Peptide Research Meta-analysis of safety data from multiple AOD 9604 trials examining injection site reactions, systemic AEs, and tolerability

Indomethacin, a potent inhibitor of 3a-hydroxysteroid dehydrogenase, a key enzyme responsible for the synthesis of allopregnanolone (ALLO) and tetradehydrodeoxycorticosterone (THDOC) (potent selective positive allosteric modulators of the GABA A receptors), has been shown to attenuate brain production of ALLO and THDOC and to improve activity in animals with CLF and mild HE [101]