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Published data show that deficiency typically emerges around 6 months post-bariatric surgery, with peak incidence at 12 months or longer (1)

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Interestingly, increased origin activation, a condition observed in cyclin E1-overexpressing cells, has been shown to reduce replication fork velocity, possibly due to depletion of factors that are essential for proper replication fork progression 54

Evidence: Large clinical programmes show meaningful weight reduction when used with lifestyle intervention, a specialist field of the RealFit Group

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Samuelson, PhD, is a senior scientist in the protein expression and modification division