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Cartilage faces even greater obstacles given avascular nature (no blood vessels penetrating tissue), low cell density (chondrocytes sparse within extensive extracellular matrix), minimal metabolic activity (slow turnover and repair), and mechanical loading challenges (constant stress impeding healing)

As of this writing, the formal FDA reclassification has been announced but not yet officially published in the Federal Register

Biochemistry, 1970, 9(23): 44864492

Here's the thing: getting older is mandatory, but feeling old doesn't have to be

Additionally, Lydium barbarum polysaccharides (LBP) scavenge free radicals and suppress oxidative stress, modulating lipid peroxidation and MDA formation while boosting SOD, and GSH-Px activity (148, 149)