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The compound requires subcutaneous administration for maximum bioavailability, as oral administration results in poor absorption due to first-pass metabolism

In the 3-KO and WT groups, male mice aged 1214 weeks were divided into three subgroups including: saline control, AOD9604 administered at a dose of 250 g/kg/day, and hGH administered at a dose of 1 mg/kg/day

Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice

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Peptide Initiative