glutathione sulfur sensitivity Frontiers Is There Really Such a

System Xc , GSH synthesis, and GPX4 have been shown to protect against cell death triggered by multiple oxidative stress responses

found that the lack of sFRP4 is one of the causes of cortical bone thinning

03 h: N = 22, 36 h: N = 15, 612 h: N = 8, 1224 h: N = 45 and 2436 h: N = 13

The cell pellet was used to prepared cytospin preps and stained with Geimsa

2 for the metabolic pathways affected by CYP450)

Glossary m Mitochondrial membrane potential 25(OH)D 25-Hydroxyvitamin D 3-HSD 3-beta-Hydroxysteroid dehydrogenase 4-HNE 4-hydroxynonenal 8-OHdG 8-hydroxy-2-deoxyguanosine ADMA Asymmetric dimethylarginine AGE Advanced glycation end products AMH Anti-Mllerian hormone AMPK Adenosine monophosphate-activated protein kinase ART Assisted reproductive technology CAT Catalase CoA Coenzyme A Cyp Cytochrome DCI D-chiro-inositol DHEA Dehydroepiandrosterone DHT Dihydrotestosterone ELISA Enzyme-linked immunosorbent assay ETC Electron transport chain FSH Follicle-stimulating hormone GF Graafian follicle GH Growth Hormone GLUT-4 Glucose transporter type 4 GPx Glutathione peroxidase GR Glutathione reductase GRAS Generally recognized as safe GSH Glutathione GSH/GSSG Reduced-to-oxidized glutathione HA Hyperandrogenism HbA1c Glycated hemoglobin HDL High-density lipoprotein HPG Hypothalamicpituitary-gonadal HPO Hypothalamic-pituitary-ovarian hs-CRP High-sensitivity C-reactive protein ICSI Intracytoplasmic sperm injection IL-10 Interleukin-10 IL-17 Interleukin-17 IL-6 Interleukin-6 IPG Inositolphosphoglycan IR Insulin resistance IRS Insulin receptor substrate IVF In vitro fertilization LDL Low-density lipoprotein LH Luteinizing hormone LPO Lipid peroxidation MAPK Mitogen-activated protein kinase MDA Malondialdehyde MI Myo-inositol MII Metaphase II MP Multilaminar primary follicle mtDNA Mitochondrial DNA NADPH Nicotinamide adenine dinucleotide phosphate NF-B Nuclear factor-kappa B NMRI Naval Medical Research Institute NO Nitric oxide NOS Nitric oxide synthase NOX NADPH oxidase NRF Nuclear related factor OCP Oral Contraceptive Pill OS Oxidative stress P Primordial follicle PCOS Polycystic ovary syndrome PI3K Phosphatidylinositol 3-kinase PPAR Peroxisome proliferator-activated receptor gamma p-STAT3 Phosphorylated signal transducer and activator of transcription 3 PUFA Polyunsaturated fatty acid RAS Renin angiotensin system ROS Reactive oxygen species RXR Retinoid X receptor SCFA Short-chain fatty acid SCN Suprachiasmatic nucleus SF Secondary follicle SHBG Sex hormone-binding globulin SOD Superoxide dismutase StAR Steroidogenic acute regulatory TAC Total antioxidant capacity TNF Tumor necrosis factor alpha TSH Thyroid-stimulating hormone UP Uilaminar primary follicle FDA United States Food and Drug Administration VDR Vitamin D receptor VDRE Vitamin D response elements VLDL Very low-density lipoprotein WHO World Health Organization References 1 SuPChenCSunY