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244 The PI3K/AKT signaling pathway The PI3K/AKT pathway is an important cell signaling pathway that plays a key role in regulating various biological processes, such as cell proliferation, apoptosis, and metabolism

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The specimens were processed on paraffin wax, and 5-m-thick paraffin sections were obtained and stained with hematoxylin and eosin or immunohistochemically for FVIII (Dako, Glostrup, Denmark) using Dako Autostainer, according to the manufacturers protocols

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