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The researchers say many patients at highest risk of developing glaucoma, such as those who have elevated pressure along with other symptoms such as thin corneas or large cup/disc ratio (a measure of the part of the optic nerve visible inside the eye) should be treated with pressure-lowering drops, but those without the additional symptoms probably dont need the therapy

Subsequently, hypoxia induces tumor and stroma cells to secret multiple pro-angiogenic factors such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and matrix metalloproteinase (MMP) [17]

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