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(2024) 11:e2400305

Although adverse reactions to intravenous, intramuscular or subcutaneous injection of 0.9% benzyl alcohol are not known to occur in man, experimental studies of small volume parenteral preparations containing 0.9% benzyl alcohol in several species of animals have indicated that an estimated intravenous dose up to 30 mL may be safely given to an adult without toxic effects

Acknowledgments The work was performed under the CNCSIS grant PD 132/30.07.2010 (PD 29/2010)

Not willing to give up, Holst turned to Thue Schwartz, a young Danish medical student and molecular pharmacologist working with Rehfeld on gastrin and new peptides isolated from the pancreas

In primary epithelial ovarian cancer (EOC) specimens, SHMT1 and SHMT2 expression is markedly elevated, and combining chemotherapy with SHMT inhibitors demonstrates potent antitumor efficacy [84]

Increased mitochondrial fission is critical for hypoxia-induced pancreatic beta cell death