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Circu and Aw, 2012

Fiber and prebiotics: mechanisms and health benefits

To overcome this limitation, Lohman and Remington (2008) further engineered roGFP1 by replacing the chromophore-interacting H148 by serine and inserting an additional amino acid between the disulfide forming C147 and S148

Mitochondrial diseases are characterized by both a diminished capacity to produce ATP as well as an elevated production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) [3]

These estimated half-lives for protein-SOHs are on par with the cellular lifetimes for many other post-translational modifications, including phosphorylation and O-GlcNAc (the half-lives for some of which are estimated to be less than 1 min) [188]

Third, our study was a multicenter prospective trial, which enhances the quality of evidence obtained compared to previous studies