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On the reproductive axis, recent meta-analyses and RCTs suggest modest improvements in ovulation-induction pregnancy rates and androgen milieu, with reductions in LH and total testosterone in some studies (123)

The intracellular cysteine pool is suggested to be maintained by at least three sources: import through alanine/serine/cysteine/threonine transporter 1 (ASCT1), uptake of cystine through system x c - (xCT and CD98) and subsequent reduction by thioredoxin reductase (TXNRD1), and de novo synthesis from methionine through the transsulfuration pathway

Cell 71 PergolaP

May 2012;94(5):1172-1179

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How fibroblasts migrate depends on ECM stiffness, the topography they encounter, and various growth factors and intracellular signaling pathways that regulate cytoskeletal reorganization and cell adhesion