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Although the competitive binding mechanism at the non-canonical site remains to be fully elucidated, our structural data show that the phosphate backbone of CTP shares binding pockets with UTP and ATP, highlighting a conserved mechanism of ligand recognition and stabilization across species

TABLE 2 SQOR-Mediated Ferroptosis Defense Across Diseases: Shared Mechanisms, Context-Specific Roles, and Positive/Negative Effects SQORmediated ferroptosis defence and context-specific roles

Mohr, P

[95] demonstrated that MDA mediates the oxidation of cartilage collagens