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used TCGA, The University of Alabama at Birmingham Cancer (UALCAN), KaplanMeier plotter, The Breast cancer Gene-Expression Miner v4.7 (bc-GenExMiner v4.7), cBioPortal, STRING, Enrichr, MethSurv, and Tumor IMmune Estimation Resource (TIMER) for bioinformatics analysis, to find that high levels of CCL 4/5/14/19/21/22 were associated with better overall survival (OS) and recurrence-free survival (RFS), while elevated expression of CCL 24 was associated with shorter OS in BC patients

10.1042/cs19990235 Clin

In addition, in response to oxidative stress, lung epithelial cells predominantly release pro-inflammatory cytokines, including IL-6, IL-10, IL-1, and TNF- (Figure 1)

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However, its associated side effects are not solely attributable to drug toxicity but also reflect intrinsic limitations of the ferroptosis mechanism itselfit can effectively kill cancer cells but may likewise damage normal high-metabolic tissues and immune cells

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