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Novel delivery systems, such as mifepristone-loaded nanostructured lipid carriers (NLCs), have been developed as an effective strategy for endometriosis-targeted therapy (136, 137)

Vegan and vegetarian athletes almost certainly need supplementation, as do those over 50 whose absorption naturally declines

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This observation aligns with intra-follicular endocrinology and intracrinology: the follicle is not a passive recipient of circulating signals, but actively shapes a compartmentalized steroid milieu through coordinated theca-granulosa steroidogenesis and local enzymatic conversion [252,253,254]