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WT mice were unilaterally injected with AAV- hSyn - SNCA or - GPX4 into the substantia nigra as described above to obtain strains overexpress human -synuclein, GPX4, or both

Fulvic acid keeps iron in a soluble state and increases the amount entering the bloodstream by a lot [19]

The viability of HK-II, intracellular lactate, and intracellular ATP were measured by the Glucokinase Activity Assay Kit, Lactic Acid Content Test Kit, and the Enhanced ATP Assay Kit according to standard protocols, respectively

Both Pro and GB are potential osmoprotectants and they are mostly studied in plants grown under salinity and drought stress

COVID-19 viral RNA and antigens have been detected in the cerebrospinal fluid and the brain tissue, indicating that the virus can cross the bloodbrain barrier to invade the central nervous system ( via extracellular vesicles and direct intercellular transmission ( The COVID-19 virus can colonize the brain, leading to neuronal death and inflammation ( COVID-19 can induce cytokine storms and neuroinflammation, leading to neuronal damage and decreased cognitive function

In other embodiments, the oligonucleotide has one to seven, one to five, or one to three phosphodiester linkages