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Distinguished features of SOD3 include: Contains copper and zinc as cofactors, similar to SOD1 Forms a homotetramer with a high affinity for heparin and other glycosaminoglycans Particularly abundant in blood vessels, lungs, and kidneys Plays a crucial role in protecting the extracellular matrix and cell surfaces Important for vascular health and blood pressure regulation SOD3's extracellular location makes it especially relevant for protecting against oxidative stress in the vascular system, where it helps maintain endothelial function and vascular tone

CLINICAL PHARMACOLOGY Water is an essential constituent of all body tissues and accounts for approximately 70% of total body weight

10.1016/j.foodchem.2021.129721 54 KulkarniM.SawantN.KolapkarA.HuprikarA.DesaiN

In general, according to the results of various studies, it seems that cyclic ACPs have better anti-cancer and less toxicity than other ACPs

Sun Q-A, Kirnarsky L, Sherman S, Gladyshev VN (2001) Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems

Matsui H, Takahashi R