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Zhai, W

Cellular studies demonstrate increased lipolysis and fatty acid oxidation in differentiated adipocytes Animal models show reduced diet-induced obesity and improved insulin sensitivity with NNMT inhibition NAD+ metabolomics studies confirm restoration of cellular NAD+ and SAMe pools following NNMT blockade These findings are based on preclinical and clinical research

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Altered physiology of gastrointestinal vagal afferents following neurotrauma

We need a much better understanding of the microbiome to create a tipping point for routine use in clinical care

& Garg, A