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For instance, intestinal tight junction disruption and gut epithelial barrier leakage have been considered as key pathogenic factors in IBD

Strict vegetarians and vegans who do not consume plant foods fortified with vitamin B12 need to consider taking a dietary supplement that contains vitamin B12 and should discuss the need for B12 supplementation with their physician

In mammals, the regulation of mitophagy appears to be more complex, both ubiquitin-mediated and receptor-mediated pathways have been described in response to mitophagy

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