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Gradient elution was performed starting at a mobile phase composition of 99% solvent A and 1% solvent B, where solvent A consisted of 5 mM ammonium acetate with 0.1% acetic acid adjusted to pH 3.5, and solvent B was acetonitrile

Using these and copper peptides together, especially at higher concentrations of either, compounds irritation risk

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Studies comparing KPV with core MSH peptides reveal distinct anti-inflammatory mechanisms