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Recent advances have shown that lncRNAs play crucial roles in the pathologys of IR and diabetes

In support of this hypothesis, diminished expression of STIM and Orai proteins has been shown to be at the origin of decreased SOCE and increased resistance to oxidative damage in HT22 cells (Rao et al., 2013)

Its like buying a pre-built house, having the delivery company take it apart into individual bricks at your driveway, and then hiring a crew to put it back together

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Kelly D, Coen RF, Akuffo KO et al (2015) Cognitive function and its relationship with macular pigment optical density and serum concentrations of its constituent carotenoids

Though they are rare they still can occur