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Flavonoids have antioxidant, anti-inflammatory, antibacterial, and antitumor properties

Sodium tanshinone IIA sulfonate protects against hyperhomocysteine-induced vascular endothelial injury via activation of NNMT/SIRT1-mediated NRF2/HO-1 and AKT/MAPKs signaling in human umbilical vascular endothelial cells

Zhang C, Xie Y, Chen H et al (2020) FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice

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A previous study investigated whether piperine (PIP) could sensitize TNBC cells to the chemotherapy drug doxorubicin (DOX)

doi: 10.1073/pnas.1705327114 192 JansenCSProkhnevskaNMasterVASandaMGCarlisleJWBilenMAet al