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How Topical GHK-Cu May Work (Mechanisms) 1) Extracellular matrix (ECM) remodeling In vitro, ex vivo, and small clinical contexts, GHK-Cu has been reported to support collagen I/III , elastin , and glycosaminoglycan synthesis and to modulate MMP/TIMP activitypathways central to dermal structure and resilience (PubMed

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Li X, Guo H, Zhao L, Wang B, Liu H, Yue L, et al