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While both have the name glutathione peroxidase, C-Gpxs actually use thioredoxin (Trx) rather than glutathione (GSH)

For example, in muscle, IRS-1 is more related to glucose uptake whereas IRS-2 stimulates the MAPK pathway [121]

[DOI] [Google Scholar] Philippe G., Angenot L

Anyone considering IV therapy should undergo screening for conditions like glucose 6 phosphate dehydrogenase (G6PD) deficiency, kidney problems, and iron overload

Nutrients 13(9):3163 Garbarino VR, Orr ME, Rodriguez KA, Buffenstein R (2015) Mechanisms of oxidative stress resistance in the brain: lessons learned from hypoxia tolerant extremophilic vertebrates