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doi: 10.3390/pharmaceutics12050463 88 TeeranachaideekulVBoonmePSoutoEBMllerRHJunyaprasertVB

Drinking both grape juices led to significantly increased glutathione and glutathione peroxidase compared with water [23,24]

Abbreviations CTR1: copper transporter 1 EOC: epithelial ovarian carcinoma ERK: extracellular signal regulated kinase FASN: fatty acid synthase JNK: c-Jun N terminal kinase MAPK: mitogen activated protein kinase PARP: poly (ADP) polymerase RSK: ribosomal s6 kinase References Chen X, Wu Y, Dong H, Zhang CY, Zhang Y

Regarding metabolic regulation, hepatocyte growth factor (HGF) secreted by MenSCs downregulates hepatic Rnf186 expression and modulates the AMPK-mTOR signaling pathway, improving glucose and lipid metabolism

BA also regulates the cholesterol metabolic pathway, allowing cholesterol to be eliminated as a water-soluble product and impaired regulation can lead to an inflammatory response that can exacerbate the development of MASLD (79)