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J Mass Spectrom Soc Jpn 50:223225

This can be explained by the fact, that superoxide radical is necessary to achieve redox cycling of metal ions (Halliwell and Gutteridge 1990)

Overall, glutathiones neuroprotective efficacy in the CNS is intricately regulated by enzyme expression, metabolic substrate availability, and regional brain biochemistry, making it a pivotal target for intervention in oxidative stress-related neuropathologies