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ICH Q7 describes written procedures for receipt, identification, quarantine, storage, handling, sampling, testing, and approval or rejection of materials [15]

Of the 632 patients referred, 132 (21%) died prior to potential listing, 372 (59%) were listed, and 263 (42%) underwent LT

PEM is characterised by a worsening of symptoms, which may be delayed, following cognitive or physical exertion that was tolerated before disease onset, such as difficulty breathing, sleeping, headaches, and severe tiredness, with a slow return to baseline not caused by sedentary lifestyle or deconditioning [10, 11]

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Cysteinyl-tRNA synthetase (CARS) controls endogenous hydropersulfide production and mitochondrial respiration

Moison RM, van Hoof EJ, Clahsen PC, van Zoeren-Grobben D, Berger HM