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While acknowledging the strengths of the study, such as participant criteria, low drop-out rates and high adherence, the researchers also acknowledged limitations, including the relatively short intervention duration and the absence of a third intervention group receiving synbiotics alongside a placebo

PMID: 1618682

Rho recommends sticking with it for at least 60 days for optimal results, which is why they back it with a 60-day money-back guarantee

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The peptide also increased expression of beta-3 adrenergic receptor RNA in fat cells of obese mice to levels comparable with lean mice, suggesting it helps normalize the fat-burning machinery that obesity suppresses