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This cycle is initiated by oxidative stress, further amplified through inflammation driven by the TLR/NF-B pathway, and exacerbated by the suppression of protective mechanisms such as the Nrf2 pathway

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This bidirectional cycle between oxidative stress and diabetes underscores the need to examine contributing factors, notably diet, which significantly influences both

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Specific vitamins, including B-complex vitamins (B1, B6, B9, B12), vitamin D, and antioxidants (C, E), demonstrate therapeutic potential through mechanisms ranging from neurotransmitter regulation to mitochondrial function enhancement