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For instance, firefighters are at a greater risk of developing several types of cancer because of the constant exposure to smoke and other hazardous materials (303)(304)

While it is unsurprising that many ALS symptoms are related to signs of copper deficiency, resulting in vascular, antioxidant system and mitochondrial oxidative respiration deficiencies, there are also signs of copper toxicity such as ROS generation and enhanced protein aggregation

10.3389/fmed.2017.00224 61

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Neuroinflammation and neuronal loss Copper ion overload can directly cause neuronal damage or death, accelerating the pathological process of AD (9)

doi: 10.1016/j.xcrm.2020.100146 170 ZhaoZZhangZLiJDongQXiongJLiYet al