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This acute footshock paradigm is widely used to model trauma-induced fear and anxiety in rodents and is often referred to as a PTSD-like or contextual fear model ( 2.3 Open field test The open field test is commonly used to measure locomotor and anxiety-like behavior in mice ( Outcomes included average movement speed, time spent in the central squares (inner zone), and number of fecal boli

Over the past 20 years, abnormal GST expression has been linked to the occurrence of tumor resistance to chemotherapy drugs, demonstrating that this enzyme possesses functions beyond metabolism

After just one week on this protocol, patients start to notice a dramatic increase in the quality of their sleep

Aliment Pharmacol Ther 27:104119 Li L, Hua Y, Ren J (2012) Short-chain fatty acid propionate alleviates Akt2 knockout-induced myocardial contractile dysfunction

These results suggested that in the cellular context, the ASXL1 1-645 cancer-linked truncation variant shows an increased ability to bridge BRD4 to some ASXL1-regulated genes, and the ASXL1 1-591 truncation may be less efficient in linking BRD4