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Description

Novel CHOP activator LGH00168 inhibits the NF-B pathway and induces ROS-mediated ER stress, leading to necroptosis in A549 human lung cancer cells (177)

Rahim ATMA, Takahashi Y, Yamaki K

Youssef OM, et al

It is characterized by chronic dysfunction of the RPE, accumulation of drusen beneath the RPE, and progressive atrophy of the underlying choriocapillaris, which provides oxygen and nutrients to photoreceptor cells