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Although IV and oral acetylcysteine are equally effective for this indication, oral administration is generally poorly tolerated due to the higher dosing required to overcome its low oral bioavailability, [26] its foul taste and odor, and a higher incidence of adverse effects when taken orally, particularly nausea and vomiting

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New Phytol 209(2):762772 Dixit G, Singh AP, Kumar A, Mishra S, Dwivedi S, Kumar S, Trivedi PK, Pandey V, Tripathi RD (2016) Reduced arsenic accumulation in rice (Oryza sativa L.) shoot involves sulfur mediated improved thiol metabolism, antioxidant system and altered arsenic transporters