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Quinone species are arguably the most renowned redox cyclers and are pivotal to many biological mechanisms 3

To purify Flag-Strep ASXL1, nuclear extracts were incubated overnight at 4 C on rotator with anti-Flag M2 agarose (Sigma-Aldrich) in wash buffer, 50 mM TrisHCl, pH 7.3, 150 mM KCl, 5 mM MgCl 2 , 0.2 mM EDTA, 10% glycerol, 0.1% Tween, 2 mM -mercaptoethanol, 0.25 mM PMSF and proteases inhibitors (Sigma)

To view a copy of this license, visit About this article Cite this article Bai, Y., Li, K., Li, X

Five patients excluded from the study, three of them died before the end of the study and the other 2 patients received NAC dosage other than the study protocol

However, for general health and cosmetic goals, its benefits remain largely unproven, and the potential risks cannot be ignored

Genetic factors such as SNPs in selenoproteins were identified to be risk factors for OA development