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Methylcobalamin can reduce pain in chronic neuropathic pain by decreasing dorsal root ganglion (DRG) neuron excitability and suppressing the hyperpolarization-activated cation current (Ih) in medium-sized DRG neurons

Congenital transport-protein deficiencies, including transcobalamin II deficiency, are another rare cause of vitamin B 12 deficiency

Gentle massage around the area not directly on it can help too, and if it's sore, over-the-counter pain relief may do the trick

End-users may either ingest it directly via oral administration or blend it into assorted drinks and daily beverages without pre-dissolving procedures